2026 Lexus ES 350e (21 inch Wheels) MPG & Specs — Real Fuel Cost
Quick answer
The 2026 Lexus ES 350e (21 inch Wheels) gets an EPA-estimated 129/112 MPG (city/highway) and 121 MPG combined, with an estimated $600/year fuel cost.
The 2026 Lexus ES 350e (21 inch Wheels) with the listed electricity engine returns an EPA-estimated 129 MPG in the city and 112 MPG on the highway, for a combined 121 MPG. This page summarizes the official EPA fuel-economy and emissions data for this configuration.
| Engine | — |
| Transmission | Automatic (A1) |
| Drive | Front-Wheel Drive |
| Fuel type | Electricity |
| Vehicle class | Midsize Cars |
| MPG — city | 129 |
| MPG — highway | 112 |
| MPG — combined | 121 |
| Annual fuel cost* | $600 |
| CO₂ tailpipe | — |
| EPA GHG score | 10/10 |
| Electric range | 292 mi |
How efficient is it?
As an all-electric vehicle, the 2026 Lexus ES 350e (21 inch Wheels) is rated in MPGe rather than MPG, and running costs are dominated by electricity rather than fuel. That is about 374% better than the typical Midsize Cars of its era (26 MPG class average), making it one of the more efficient choices in its class.
Fuel economy and running costs
At about $600 per year in fuel (EPA estimate, 15,000 mi/yr), fuel is a major part of the cost of owning the 2026 Lexus ES 350e (21 inch Wheels). Over five years that is roughly $3,000 at today's prices — before insurance, maintenance, and depreciation.
How to read these numbers
EPA figures come from standardized laboratory test cycles and are the same estimates shown on the vehicle's window sticker. Your real-world mileage depends on driving style, conditions, fuel grade, and maintenance. Use combined MPG and annual fuel cost to compare vehicles fairly.