2022 Mercedes-Benz EQS 450 Plus MPG & Specs — Real Fuel Cost
Quick answer
The 2022 Mercedes-Benz EQS 450 Plus gets an EPA-estimated 97/97 MPG (city/highway) and 97 MPG combined, with an estimated $800/year fuel cost.
The 2022 Mercedes-Benz EQS 450 Plus with the listed electricity engine returns an EPA-estimated 97 MPG in the city and 97 MPG on the highway, for a combined 97 MPG. This page summarizes the official EPA fuel-economy and emissions data for this configuration.
| Engine | — |
| Transmission | Automatic (A1) |
| Drive | Rear-Wheel Drive |
| Fuel type | Electricity |
| Vehicle class | Large Cars |
| MPG — city | 97 |
| MPG — highway | 97 |
| MPG — combined | 97 |
| Annual fuel cost* | $800 |
| CO₂ tailpipe | — |
| EPA GHG score | 10/10 |
| Electric range | 350 mi |
How efficient is it?
As an all-electric vehicle, the 2022 Mercedes-Benz EQS 450 Plus is rated in MPGe rather than MPG, and running costs are dominated by electricity rather than fuel. That is about 271% better than the typical Large Cars of its era (26 MPG class average), making it one of the more efficient choices in its class.
Fuel economy and running costs
At about $800 per year in fuel (EPA estimate, 15,000 mi/yr), fuel is a major part of the cost of owning the 2022 Mercedes-Benz EQS 450 Plus. Over five years that is roughly $4,000 at today's prices — before insurance, maintenance, and depreciation.
How to read these numbers
EPA figures come from standardized laboratory test cycles and are the same estimates shown on the vehicle's window sticker. Your real-world mileage depends on driving style, conditions, fuel grade, and maintenance. Use combined MPG and annual fuel cost to compare vehicles fairly.