2017 Mercedes-Benz E400 4matic (station wagon) MPG & Specs — Real Fuel Cost
Quick answer
The 2017 Mercedes-Benz E400 4matic (station wagon) gets an EPA-estimated 19/25 MPG (city/highway) and 21 MPG combined, with an estimated $3,600/year fuel cost and 417 g/mi CO₂. Engine: 3 L 6-cyl.
The 2017 Mercedes-Benz E400 4matic (station wagon) with the 3-liter 6-cylinder premium gasoline engine returns an EPA-estimated 19 MPG in the city and 25 MPG on the highway, for a combined 21 MPG. This page summarizes the official EPA fuel-economy and emissions data for this configuration.
| Engine | 3 L 6-cyl |
| Transmission | Automatic 9-spd |
| Drive | 4-Wheel Drive |
| Fuel type | Premium Gasoline |
| Vehicle class | Midsize Station Wagons |
| MPG — city | 19 |
| MPG — highway | 25 |
| MPG — combined | 21 |
| Annual fuel cost* | $3,600 |
| CO₂ tailpipe | 417 g/mi |
| EPA GHG score | 4/10 |
How efficient is it?
With a combined 21 MPG, the 2017 Mercedes-Benz E400 4matic (station wagon) sits in the moderate range for fuel economy. That is about average for its class (Midsize Station Wagons, 22 MPG average).
Fuel economy and running costs
At about $3,600 per year in fuel (EPA estimate, 15,000 mi/yr), fuel is a major part of the cost of owning the 2017 Mercedes-Benz E400 4matic (station wagon). Over five years that is roughly $18,000 at today's prices — before insurance, maintenance, and depreciation.
Emissions
The 2017 Mercedes-Benz E400 4matic (station wagon) emits approximately 417 grams of CO₂ per mile at the tailpipe, earning an EPA greenhouse-gas score of 4 out of 10. Lower emissions generally track higher fuel economy.
How to read these numbers
EPA figures come from standardized laboratory test cycles and are the same estimates shown on the vehicle's window sticker. Your real-world mileage depends on driving style, conditions, fuel grade, and maintenance. Use combined MPG and annual fuel cost to compare vehicles fairly.