2006 Mercedes-Benz E320 Cdi MPG & Specs — Real Fuel Cost
Quick answer
The 2006 Mercedes-Benz E320 Cdi gets an EPA-estimated 23/33 MPG (city/highway) and 27 MPG combined, with an estimated $2,950/year fuel cost and 377.037 g/mi CO₂. Engine: 3.2 L 6-cyl.
The 2006 Mercedes-Benz E320 Cdi with the 3.2-liter 6-cylinder diesel engine returns an EPA-estimated 23 MPG in the city and 33 MPG on the highway, for a combined 27 MPG. This page summarizes the official EPA fuel-economy and emissions data for this configuration.
| Engine | 3.2 L 6-cyl |
| Transmission | Automatic 5-spd |
| Drive | Rear-Wheel Drive |
| Fuel type | Diesel |
| Vehicle class | Midsize Cars |
| MPG — city | 23 |
| MPG — highway | 33 |
| MPG — combined | 27 |
| Annual fuel cost* | $2,950 |
| CO₂ tailpipe | 377.037 g/mi |
| EPA GHG score | — |
How efficient is it?
With a combined 27 MPG, the 2006 Mercedes-Benz E320 Cdi sits in the good range for fuel economy. That is about average for its class (Midsize Cars, 26 MPG average).
Fuel economy and running costs
At about $2,950 per year in fuel (EPA estimate, 15,000 mi/yr), fuel is a major part of the cost of owning the 2006 Mercedes-Benz E320 Cdi. Over five years that is roughly $14,750 at today's prices — before insurance, maintenance, and depreciation.
Emissions
The 2006 Mercedes-Benz E320 Cdi emits approximately 377.037 grams of CO₂ per mile at the tailpipe. Lower emissions generally track higher fuel economy.
How to read these numbers
EPA figures come from standardized laboratory test cycles and are the same estimates shown on the vehicle's window sticker. Your real-world mileage depends on driving style, conditions, fuel grade, and maintenance. Use combined MPG and annual fuel cost to compare vehicles fairly.